Status:

COMPLETED

Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)

Lead Sponsor:

Incyte Corporation

Conditions:

MPN (Myeloproliferative Neoplasms)

Eligibility:

All Genders

18+ years

Brief Summary

This is a Phase IV, multicenter, non-interventional, non-randomized, prospective, observational study in an adult population (patients \>18 years old) of men and women who have been diagnosed with cli...

Eligibility Criteria

Inclusion

  • Age ≥18 years
  • Diagnosis of Polycythemia Vera (PV)
  • Willing and able to provide written informed consent
  • Willing and able to complete patient assessment questionnaires either alone or with minimal assistance from a caregiver and/or trained site personnel
  • Under the supervision of a physician for the current care of PV including but not limited to watchful waiting, acetylsalicylic acid (ASA) 81mg or greater, antithrombotic therapy, Phlebotomy (PHL), Hydroxyurea (HU), interferon (recombinant or pegylated), busulfan, anagrelide

Exclusion

  • Participation in an active clinical trial in which the study treatment is blinded
  • Life expectancy \<6 months
  • Diagnosis of myelofibrosis (MF) \[including primary MF, post-PV MF, or post-essential thrombocythemia MF (post-ET MF)\]
  • Diagnosis of secondary Acute Myeloid Leukemia (AML)
  • Diagnosis of Myelodysplastic Syndrome (MDS)
  • History of or active plan to proceed to allogeneic hematopoietic stem cell transplant in next 3 months
  • Splenectomy

Key Trial Info

Start Date :

July 31 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 3 2019

Estimated Enrollment :

2544 Patients enrolled

Trial Details

Trial ID

NCT02252159

Start Date

July 31 2014

End Date

August 3 2019

Last Update

April 26 2021

Active Locations (266)

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Page 1 of 67 (266 locations)

1

Green Valley, Arizona, United States

2

Safford, Arizona, United States

3

Scottsdale, Arizona, United States

4

Tucson, Arizona, United States