Status:
COMPLETED
Study of the Diagnostic Value of Stable Calcium Isotope Profiling in Bone and Calcium Disorders
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Collaborating Sponsors:
GEOMAR-Helmholtz Centre for Ocean Research
Conditions:
Bone Diseases
Osteomalacia
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to determine whether mass spectrometry analysis of stable (non-radioactive) calcium isotopes in plasma or urine samples can help in the diagnosis of bone and calcium disor...
Detailed Description
The aim of this pilot study is to explore the diagnostic value of MC-ICP-MS (multicollector inductively coupled plasma mass spectrometry) or TIMS (thermal ionization mass spectrometry) measurement of ...
Eligibility Criteria
Inclusion
- DXA (dual energy X-ray absorptiometry) T-score known clinically to be = or \< -2.5 OR presence of low-energy osteoporotic fractures (i.e. excluding those of the skull, fingers and toes) \[for osteoporosis and calcium malabsorption patients\]
Exclusion
- inability to provide written informed consent
Key Trial Info
Start Date :
October 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT02252679
Start Date
October 1 2014
End Date
December 1 2018
Last Update
November 6 2020
Active Locations (2)
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1
UZ Leuven
Leuven, Belgium, 3000
2
GEOMAR-Helmholtz Centre for Ocean Research
Kiel, Germany, 24148