Status:

TERMINATED

Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections

Lead Sponsor:

Irrimax Corporation

Conditions:

Surgical Site Infection

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study was to compare the rate of surgical site infections in patients randomized to Irrisept versus SoC, who had an open abdominal laparotomy for abdominal trauma or acute surgical...

Detailed Description

The trial was explained to potential subjects, the informed consent was completed and and eligibility was verified. After this, the subjects were randomized to Irrisept or SoC and an open abdominal la...

Eligibility Criteria

Inclusion

  • Is male or female, 18 years of age or older
  • Has provided written informed consent or has surrogate consent provided by a Legally Authorized Representative (LAR)
  • Has experienced abdominal trauma, blunt or penetrating, requiring open abdominal laparotomy with primary closure or
  • Has experienced acute surgical abdomen requiring open abdominal laparotomy with primary closure

Exclusion

  • Known allergy to Chlorhexidine Gluconate (CHG)
  • Estimated Abbreviated Injury Scale (AIS) score of six (6) at the time of surgery, for all trauma patients
  • American Society of Anesthesiologists Physical Status Classification (ASA) score of five (5) or greater (As ASA scoring is a subjective measure, if the PI finds the patient stable enough for study participation despite a score of 5, enrollment may continue.)
  • Female volunteers who are pregnant and/or breast feeding
  • Damage control laparotomy
  • Abdominal incision created prior to operating room (i.e. incision made in trauma bay to cross clamp the aorta)
  • Currently enrolled in an ongoing, interventional, randomized clinical trial

Key Trial Info

Start Date :

February 18 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 13 2017

Estimated Enrollment :

627 Patients enrolled

Trial Details

Trial ID

NCT02255487

Start Date

February 18 2015

End Date

March 13 2017

Last Update

May 24 2022

Active Locations (17)

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Page 1 of 5 (17 locations)

1

The University of Arizona

Tucson, Arizona, United States, 85724

2

The University of Southern California, USC Medical Center

Los Angeles, California, United States, 90033

3

Denver Health and Hospital Authority

Denver, Colorado, United States, 80204

4

The University of South Florida, Tampa General Hospital

Tampa, Florida, United States, 33606

Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections | DecenTrialz