Status:
COMPLETED
Effect of Inspiratory Muscle Training on Exercise Performance and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease
Lead Sponsor:
Mansoura University
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
MALE
45-65 years
Phase:
NA
Brief Summary
The aim is to study effectiveness of inspiratory muscle training as a part of exercise training in patients with Chronic Obstructive Pulmonary Disease (COPD) and if it adds to general exercise trainin...
Eligibility Criteria
Inclusion
- Exsmokers
- Low PImax compared to reference values \[lower limits of normal: 80 cmH2O for patients less than or equal 54 years old; 71 cmH2O for patients' age between 55-64 years; and 65 cmH2O for patients 65 years old \].
- Stable patients without history of exacerbation or hospitalization four weeks before starting the study.
Exclusion
- Lack of motivation and compliance.
- Patients with significant reversibility following bronchodilation defined as an increase in FEV1 of more than 12% and 200 ml from the pre-bronchodilator value
- Unstable cardiac disease \[severe heart failure, dangerous dysrhythmias, recent myocardial infarction or unstable angina (within 4 weeks)\].
- Uncontrolled hypertension
- Recent pneumothorax (within 6 weeks)
- Recent abdominal or thoracic surgery (within 6 weeks)
- Known progressive neuromuscular disorders
- Recent gastrointestinal bleeding (within 4 weeks)
- Current smokers
- Active cancer
- Patients with advanced liver diseases, or renal impairment.
- Known connective tissue diseases
- Significant endocrinal abnormalities
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02257463
Start Date
October 1 2011
End Date
April 1 2014
Last Update
April 8 2015
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