Status:

COMPLETED

Trial Comparing Intensity Modulated Radiotherapy Versus Conformal Radiotherapy to Treat Prostate Cancer With Hypofractionated Schedule

Lead Sponsor:

Gustavo Viani Arruda

Conditions:

Prostate Cancer

Eligibility:

MALE

18-75 years

Phase:

PHASE3

Brief Summary

There is no randomized controlled trial (RCT) comparing Conformal Radiotherapy (3DCRT) versus the Intensity Modulated Radiotherapy (IMRT) in terms of toxicity and disease control. Data from retrospect...

Eligibility Criteria

Inclusion

  • Patients with diagnosis of prostate cancer
  • With age between 18-75 years classified in low
  • Intermediate and high-risk group according to their Gleason score
  • T stage and initial PSA (iPSA).
  • Low risk group included patients with Gleason score \<7 / stage T1-T2a, and iPSA \<10 ng/mL.
  • Intermediate risk included Gleason score \< 7, or Stage T1-T2b, or iPSA level of 10-20 ng/mL
  • High-risk patients with Gleason score \>7, or Stage \> T2b, or iPSA \>20 ng/mL.
  • All patients classified as high risk was submitted to the bone scans.

Exclusion

  • Patients with metastases
  • Prior history of prostatectomy
  • Pelvic radiotherapy treatment
  • Chemotherapy treatment were excluded of this trial.

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2013

Estimated Enrollment :

220 Patients enrolled

Trial Details

Trial ID

NCT02257827

Start Date

January 1 2009

End Date

January 1 2013

Last Update

October 6 2014

Active Locations (1)

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Faculty of Medicine of Marilia

Marília, São Paulo, Brazil