Status:
COMPLETED
Identify Bacteria Associated With Metabolic Diseases That Reside Both in Intestinal Crypts and in Blood
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Obesity
Eligibility:
All Genders
35-75 years
Phase:
NA
Brief Summary
The investigators will compare 16sRDNA profile in cases and controls in order to identify bacteria associated with metabolic diseases that reside both in intestinal crypts and in blood.
Detailed Description
Experimental evidence suggests that bacterial translocation from gut to tissue could be an initial step leading to diabetes. To test this hypothesis, a bacterial component that is highly conserved bet...
Eligibility Criteria
Inclusion
- Between 35 and 75 years old
- Colonoscopy and biopsies required
- Diabetes population:
- Type 2 diabetes
- Obese population:
- Android obesity
Exclusion
- Inflammatory bowel disease
- Colonic cancer
- Bariatric surgery
- Previous administration of antibiotic (within 15 days)
- Pregnancy
Key Trial Info
Start Date :
February 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT02261831
Start Date
February 1 2014
End Date
December 1 2017
Last Update
December 3 2018
Active Locations (1)
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1
University Hospital of Toulouse
Toulouse, France, 31 052