Status:

WITHDRAWN

Resveratrol and Human Hepatocyte Function in Cancer

Lead Sponsor:

University of Louisville

Conditions:

Liver Cancer

Eligibility:

All Genders

21-80 years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of this study is to determine if Resveratrol, a nutritional supplement, shows a beneficial effect in the cellular function of normal liver cells and diseased liver cells (cancer cells) in ...

Detailed Description

Hepatic function will be assessed by standard laboratory techniques. Hepatocyte signaling pathway proteins will be measured using western blot analysis for protein expression and polymerase chain reac...

Eligibility Criteria

Inclusion

  • Undergoing elective liver resection for liver cancer

Exclusion

  • Inability to speak or read English
  • Sclerosing cholangitis, hemochromatosis, hepatic encephalopathy, acute hepatic failure
  • History of daily alcohol intake
  • Presence of human immunodeficiency virus
  • Presence of significant renal dysfunction as defined by baseline serum creatinine \> 2.0 mg/dl or need/impending need for chronic dialysis therapy
  • Known allergy to the study medication
  • Pregnancy, lactating women, women contemplating pregnancy during the study period

Key Trial Info

Start Date :

December 1 2015

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT02261844

Start Date

December 1 2015

End Date

June 1 2016

Last Update

March 30 2017

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Louisville

Louisville, Kentucky, United States, 40202