Status:
COMPLETED
CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients
Lead Sponsor:
El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Conditions:
Depression
Epilepsy, Temporal Lobe
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The aim of the study is to compare the effect of group-cognitive-behavioral therapy (CBT)versus treatment as usual with the selective serotonin reuptake inhibitor sertraline, in patients with diagnosi...
Detailed Description
patients with temporal lobe epilepsy and depression will be enrolled into one of two treatment modality. The first group will receive 12 group cognitive behavioral sessions. CBT is a psychotherapy foc...
Eligibility Criteria
Inclusion
- With Major depressive disorder according to criteria from the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
- Diagnosed with TLE according to the criteria of the International League Against Epilepsy
- Literates had sign an informed consent
- Patients on antidepressant treatments will be allowed to participate only if they had been at stable doses for more than 8 weeks and still show signs of significant depression
Exclusion
- Patients with high risk of suicide who required hospitalization
- Patients who abused or are dependent on drugs
- Those with a history of head trauma six months prior to the interview
- Patients who have any condition that would prevent them from understanding the study or the psychotherapeutic process, such as mental retardation, psychosis, delirium, dementia, etc
- Patients who have previously received CBT
- Patients who have started, an antidepressant drug the last 8 weeks
Key Trial Info
Start Date :
August 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT02262156
Start Date
August 1 2014
End Date
November 1 2014
Last Update
March 30 2015
Active Locations (1)
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1
Instituto Nacional de Neurología y Neurocirugía MVS
México, D.f., Mexico, 14269