Status:

COMPLETED

Thigh Pain After Total Knee Arthroplasty (TKA)

Lead Sponsor:

Fondren Orthopedic Group L.L.P.

Collaborating Sponsors:

InGeneron, Inc.

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this research study is to evaluate the cause of thigh pain after knee replacement. Different surgical techniques will be used to help determine the cause of thigh pain, and all surgical...

Detailed Description

This research study will be a randomized study in which patients volunteer participate. "Randomized" means the patients who received the new treatment are chosen at random, similar to flipping a coin....

Eligibility Criteria

Inclusion

  • Subjects undergoing total knee arthroplasty for osteoarthritis
  • Adult patients (age 18 years or older)
  • Written informed consent
  • Ability to speak, read and write English or Spanish

Exclusion

  • Inability to speak, read and write English or Spanish
  • Evidence of malignant disorder/neoplasm in past 60 months
  • Contraindication for removal of infrapatellar fat pad
  • History of smoking and not committed to give up
  • Chronic skin conditions
  • Connective, metabolic or skin disease
  • Evidence of active infection
  • Pregnancy or lactating for female subjects
  • Current corticosteroid use
  • Immunosuppressive medication
  • Renal failure (creatine \> 1.8 mg/dL)
  • Hepatic failure (AST, ALT \> 2x normal values; bilirubin \> 2 mg/dL)
  • Inflammatory joint diseases of the knee that indicate additional, conflating therapies
  • Joint infection within the past 6 months
  • No prisoners or mentally disabled persons
  • No Workers' Compensation cases

Key Trial Info

Start Date :

September 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT02262988

Start Date

September 1 2017

End Date

March 1 2021

Last Update

June 7 2022

Active Locations (1)

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Fondren Orthopedic Group, L.L.P.

Houston, Texas, United States, 77030