Status:
TERMINATED
In Vivo Alzheimer Proteomics
Lead Sponsor:
University Hospital, Montpellier
Collaborating Sponsors:
Assistance Publique - Hôpitaux de Paris
University Hospital, Clermont-Ferrand
Conditions:
Probable Alzheimer Disease
Parkinson Disease
Eligibility:
All Genders
55-85 years
Phase:
NA
Brief Summary
In France, an estimated 860 000 patients are affected by Alzheimer Disease (AD) which represents, as in other developed countries, a major public health issue. In many cases, AD diagnosis is uncertain...
Eligibility Criteria
Inclusion
- Reports written consent, informed and signed by the patient and a trusted person
- Subject member or beneficiary of a social security system
- Specific criteria for group 1 and 2B :
- Age between 55 and 85 years old for patients
- Subject with AD or other neurodegenerative disease (frontotemporal dementia, dementia with Lewy bodies, Parkinson disease)
- Subjects with chronic adult hydrocephalus (HCA) requiring depletion lumbar puncture (PL)
- Specific criteria for group 2A :
- \- Adult patient requiring neurosurgery with CSF shunt (subject with brain trauma, acute hydrocephaly) and favorable evolution that allows removal of the shunt
Exclusion
- Patient deprived of liberty by judicial or administrative decision
- Major protected by law
- Pregnancy, women of childbearing age with risk of pregnancy, or breast-feeding
- Presence of a transmissible viral disease (HlV, hepatitis B and C)
- Patient included in a clinical trial
- lnadequate cardiac, hepatic or severe renal disfunction
- Disease amino acid metabolism (Leucinose..)
Key Trial Info
Start Date :
October 8 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 22 2018
Estimated Enrollment :
89 Patients enrolled
Trial Details
Trial ID
NCT02263235
Start Date
October 8 2013
End Date
May 22 2018
Last Update
December 28 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Laboratoire de Biochimie et Protéomique Clinique, CHU Montpellier
Montpellier, France, 34295