Status:

TERMINATED

LESCOD: "Lewy Body Screening in Cognitive Disorders"

Lead Sponsor:

Nantes University Hospital

Conditions:

Alzheimer Disease

Lewy Body Disease

Eligibility:

All Genders

60-90 years

Phase:

NA

Brief Summary

Dementia with Lewy body (DLB) is the second most common neurodegenerative dementia in autopsy series. However, DLB represents a small proportion of the clinical diagnoses in epidemiology registries. I...

Eligibility Criteria

Inclusion

  • Be a woman or a male \>60 to \< 90 years
  • Have sufficient visual and auditory acuity
  • Be able to speak, read, hear and understand french language
  • Be covered by health care insurance
  • Have a reliable help/partner/informant/caregiver
  • Have a mild to severe cognitive decline based on MMSE (Mini-Mental State Examination) score ( From 18 to 26)
  • Give oral agreement to the assessment of the LEsCoD scale during routine consultation
  • Have performed neuropsychology tests and MRI respectively within 6 and 12 months

Exclusion

  • Has evidence of neurological or psychiatric disorder other than AD or DLB explaining cognitive decline
  • Has received previously or currently neuroleptic treatment
  • Has no reliable help/caregiver the day of the visit
  • Refuses to give his/her oral agreement to the assessment of the LeSCoD scale
  • Has presence on MRI of radiologic evidence of cerebrovascular disease (score Fazekas 2)

Key Trial Info

Start Date :

October 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2017

Estimated Enrollment :

133 Patients enrolled

Trial Details

Trial ID

NCT02263287

Start Date

October 1 2014

End Date

August 1 2017

Last Update

December 7 2017

Active Locations (1)

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1

Nantes University Hospital

Nantes, France