Status:

COMPLETED

Exercise & Brain Health in MS

Lead Sponsor:

Oregon Health and Science University

Conditions:

Multiple Sclerosis

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

The purpose of this study is to learn more about multiple sclerosis (MS). The investigators are studying whether aerobic exercise is better than a stretching program at improving brain health in peopl...

Detailed Description

Multiple sclerosis (MS) is a disease of brain, spinal cord and optic nerves. Current MS therapies reduce the frequency and severity of MS flare-ups, but do not help MS in later stages of disease chara...

Eligibility Criteria

Inclusion

  • i. Physician-confirmed diagnosis of relapsing-remitting MS ii. \> 18 years old iii. Expanded Disability Status Scale (EDSS) \< 4.0 iv. Able to give informed consent

Exclusion

  • i. Current cardiopulmonary disease requiring treatment (hypertension permitted) ii. Medical or biophysical conditions that do not permit use of either a cycle ergometer or treadmill iii. MRI contraindications (pacemaker, wires, defibrillator, or implanted heart valves, head surgery requiring aneurysm clips, or any type of electric device (stimulator or pump) implanted in the body) iv. MS exacerbation in the last 30 days v. Pregnant women: Pregnancy status determined by menstrual history and contraceptive method. Confirmatory urine pregnancy test will be used if pregnancy status is uncertain

Key Trial Info

Start Date :

September 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 25 2016

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT02263339

Start Date

September 1 2014

End Date

May 25 2016

Last Update

June 19 2019

Active Locations (1)

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Oregon Health & Science University

Portland, Oregon, United States, 97239