Status:
COMPLETED
Improving Antibiotic Use in Hospitalized Patients With Pneumonia
Lead Sponsor:
Giulio DiDiodato
Conditions:
Pneumonia
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of the study is to determine whether an antimicrobial stewardship program can decrease the length of hospital stay for patients with pneumonia. The antimicrobial stewardship program is run...
Detailed Description
In immune-competent adult patients admitted to a hospital ward with a diagnosis of community-acquired pneumonia, does a multi-faceted ASP utilizing prospective chart audit and feedback compared with u...
Eligibility Criteria
Inclusion
- have a positive Febrile Respiratory Illness (FRI) screen on admission to hospital (http://www.health.gov.on.ca/fr/public/programs/emu/sars/reports/dir\_122303\_acute\_care\_nonoutbreak.pdf)
- diagnosed with pneumonia by the admitting physician (Acute exacerbations of chronic obstructive lung disease are considered within the definition of pneumonia for the purposes of this study as they are commonly treated with the same antimicrobial regimens as patients with pneumonia)
- admitted to a medical ward
Exclusion
- hospitalized for ≥ 48 consecutive hours in the preceding 3 months
- receiving immunosuppressants \[defined as ≥ 40 mg prednisone daily (or steroid equivalent) for ≥ 2 weeks preceding hospitalization OR any other immunosuppressant used for systemic illness OR to prevent transplant rejection\]
- neutropenic \[defined as a polymorphonuclear count ≤ 0.5 x 109 cells/L\] from any cause
- immunocompromised \[defined as having leukemia, lymphoma, HIV with CD4 cell count ≤ 200, splenectomy or on cytotoxic chemotherapy\]
- admitted to high acuity units such as intensive care units
- require mechanical ventilation, either non-invasive or invasive
- have a life expectancy of ≤ 3 months (palliative)
Key Trial Info
Start Date :
April 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
763 Patients enrolled
Trial Details
Trial ID
NCT02264756
Start Date
April 1 2013
End Date
April 1 2015
Last Update
January 27 2020
Active Locations (1)
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1
Royal Victoria Regional Health Centre
Barrie, Ontario, Canada, L0L2L0