Status:
COMPLETED
Fat-induced Release of GLP-1 in Humans
Lead Sponsor:
Glostrup University Hospital, Copenhagen
Collaborating Sponsors:
University of Copenhagen
Conditions:
Type 2 Diabetes
Eligibility:
MALE
18-40 years
Phase:
NA
Brief Summary
This study compared the incretin-releasing effect of C8-diet oil and tributyrin with that of 20 ml olive oil on a molar basis in human volunteers.
Detailed Description
A structured triglyceride (1,3-di-octanoyl-2-oleoyl-glycerol, called C8-diet oil), which upon digestion results in generation of two medium-chain fatty acids and 2-oleoyl-glycerol (2-OG), may lead to ...
Eligibility Criteria
Inclusion
- Caucasian healthy male subjects
- Body mass index (BMI) 19 to 25 kg/m2
- Informed consent
Exclusion
- Anaemia
- Diabetes mellitus
- Gastrointestinal diseases or operations interacting with intestinal absorption
Key Trial Info
Start Date :
October 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT02264951
Start Date
October 1 2013
End Date
February 1 2014
Last Update
October 15 2014
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