Status:
COMPLETED
Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome
Lead Sponsor:
Wake Forest University Health Sciences
Conditions:
Pulmonary Contusion
Respiratory Failure
Eligibility:
All Genders
16+ years
Brief Summary
Pulmonary contusion (PC) is a significant problem after blunt trauma that may often lead to acute respiratory distress syndrome (ARDS) and in some patients, death. Although the pathophysiology is inco...
Detailed Description
The study will be conducted at Wake Forest University Baptist Medical Center and will enroll 40 patients in the PC study group, 20 patients in each control group, and 20 MICU patients. Recruitment wil...
Eligibility Criteria
Inclusion
- Age \> 15 years old
- Chest trauma patients
- Medical ICU patients with respiratory failure
- Elective surgery patients
- Trauma or surgical ICU patients on ventilators without chest trauma/pulmonary contusion
Exclusion
- Age 15 years and younger
- Pregnant women
- Subjects with multiple myeloma, pheochromocytoma, homozygous sickle cell disease, or thyroid disorders
- Traumatic brain injury requiring intracranial pressure monitoring
- Moribund status
Key Trial Info
Start Date :
September 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT02265198
Start Date
September 1 2014
End Date
March 1 2015
Last Update
November 6 2017
Active Locations (1)
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1
Wake Forest Baptist Health
Winston-Salem, North Carolina, United States, 27157