Status:
UNKNOWN
Augmenting Treatment Effects of Voice Therapy in Parkinson Disease
Lead Sponsor:
Le Bonheur Children's Hospital
Collaborating Sponsors:
Michael J. Fox Foundation for Parkinson's Research
University of Tennessee
Conditions:
Parkinson Disease
Eligibility:
All Genders
45-80 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the impact of a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) on voice/speech treatment in people with Parkinson's Di...
Detailed Description
Effective treatment of the speech disorder in IPD is as important as the optimal control of limb motor symptoms. Presently, the Lee Silverman Voice Treatment (LSVTÒ LOUD) - is a time intensive behavio...
Eligibility Criteria
Inclusion
- Individuals with Idiopathic Parkinson's disease (IPD) between the ages of 45 and 80 years with moderate to severe hypophonia
- None or mild cognitive impairment or depression
- Stable medication therapy for at least 3 months. Must be "optimally medicated" at the start of the study. This means that there should be no change in mediction type or dosage in 3 months prior to enrolling in the study. The medications should not be causing significant or serious advese effects
Exclusion
- History of drug abuse or neurological condition other than or in addition to IPD (for example stroke)
- Individuals with advanced IPD (stage V) or who had LSVT within 3 years
- Pregnant females
- History of seizures, history of major head trauma, metal objects implanted in the head, ferrous metal filings in the eye, brain damage, inflammation of the brain, cardiac pacemaker, implanted medication pump, cardiac lines, heart disease, currently taking certain types of medication for depression or seizures (tricyclic antidepressants or neuroleptics which lower seizure threshold
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2021
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT02265315
Start Date
October 1 2014
End Date
June 30 2021
Last Update
September 22 2020
Active Locations (1)
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1
LeBonheur Children Hospital
Memphis, Tennessee, United States, 38103