Status:
UNKNOWN
Rectal Misoprostol and Blood Loss During Abdominal Hysterectomy
Lead Sponsor:
Cairo University
Conditions:
Blood Loss
Eligibility:
FEMALE
18-80 years
Phase:
PHASE3
Brief Summary
Hysterectomy, as any major operation, can cause complications, as hemorrhage which may occur in some cases and sometimes requiring blood transfusion. Recent study proved that misoprostol success in re...
Detailed Description
In this study we tried to assess the efficacy of misoprostol in minimize blood loss during hysterectomy when used as single preoperative dose via rectal route. The reduction of blood flow may be due t...
Eligibility Criteria
Inclusion
- A- Age: adult female \>18 years old. B- Any women undergoing abdominal hysterectomy. C- No contraindications to misoprostol.
Exclusion
- A -Women with any contraindications to misoprostol including heart disease, mitral stenosis , severe hypertension ( diastolic pressure over100mm Hg) , hematologic disorders (as sickle cell anemia ), glaucoma, bronchial asthma, liver disease.
- B- Known history of or active medical disorder as DM . C- Pelvic endometriosis and adnexal mass. D- Those who had undergone previous myomectomy. E- Women who received GnRH analogues and mifepristone and who are allergic to prostaglandins.
- F- Women with mental impairment or incompetent in giving consent. G- Women who don't wish to participate in the study.
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2015
Estimated Enrollment :
220 Patients enrolled
Trial Details
Trial ID
NCT02265562
Start Date
October 1 2014
End Date
June 1 2015
Last Update
October 16 2014
Active Locations (1)
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1
Cairo University hospiatl
Cairo, Egypt, 12311