Status:
COMPLETED
Response of VEGF and AT-II to HCG in PCOS
Lead Sponsor:
Nanjing University School of Medicine
Conditions:
Polycystic Ovary Syndrome
Eligibility:
FEMALE
21-35 years
Phase:
EARLY_PHASE1
Brief Summary
This research is to investigate the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-Ⅱ (AT-Ⅱ) to ovary stimulation during 24h in patients with polycystic ...
Detailed Description
After ovary stimulation, the level of VEGF in typical PCOS patients is obviously increased at the 3hs time point (p\<0.05), while there is no difference with VEGF at all other time point among the fou...
Eligibility Criteria
Inclusion
- A total of 60 women were recruited and divided into four groups by Rotterdam criteria according to three typical characters:
- biochemical characteristics of hyperandrogenism (HA)
- chronic anovulation
- polycystic ovary morphology (PCO).
Exclusion
- All women were matched for age (\<35 yr).
- All subjects were screened, and no other endocrine disturbances (thyroid, adrenal) or medical illnesses were found.
- All the patients did not have any hormonal preparation during the 3 months preceding the study.
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02265861
Start Date
January 1 2010
End Date
December 1 2012
Last Update
October 16 2014
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.