Status:

TERMINATED

Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis

Lead Sponsor:

University Hospital of Mont-Godinne

Collaborating Sponsors:

Université Catholique de Louvain

Teva Pharmaceuticals USA

Conditions:

Relapsing Remitting Multiple Sclerosis

Secondary-progressive Multiple Sclerosis

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Noninvasive brain stimulations (NIBS) will be used in MS patients with cognitive impairments to enhance their cognitive aptitudes.

Detailed Description

tDCS will be used in a sham-controlled, double-blind, randomized, cross-over control trial in MS patients suffering from cognitive impairments and/or motor deficits. After informed consent and recruit...

Eligibility Criteria

Inclusion

  • MS patients with relapsing remitting MS/secondary progression MS (based on the 2010 revised McDonald criteria)
  • Cognitive deficits
  • Motor deficits

Exclusion

  • contraindication to tDCS (seizure or epilepsy, metal in the head, …)
  • major psychiatric conditions or major depression
  • coexisting instable medical condition
  • substance or alcohol abuse
  • regular intake of drug that strongly modulate brain excitability
  • major sequels from MS preventing participation in the study
  • pregnancy

Key Trial Info

Start Date :

October 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 8 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT02266121

Start Date

October 1 2014

End Date

May 8 2023

Last Update

May 9 2023

Active Locations (1)

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1

Department of Neurology, CHU Dinant Godinne UcL Namur

Yvoir, Namur, Belgium, B-5530