Status:
COMPLETED
Hyperglycemia and Effects of Daily 100 mg Versus 200 mg of Hydrocortisone Therapy in Patients With Septic Shock
Lead Sponsor:
Srinakharinwirot University
Conditions:
Hyperglycemia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to compare hyperglycemia and other effects, include 28-day mortality and time to reversal of shock between 100 milligrams and 200 milligrams of hydrocortisone as initial d...
Detailed Description
The intervention group will be received 100 milligrams per day of hydrocortisone on the first three day the taper off, whereas the control group will be received 200 milligrams per day of hydrocortiso...
Eligibility Criteria
Inclusion
- Septic shock
- Adequate fluid resuscitation and vasopressor therapy are unable to maintain hemodynamic stability
Exclusion
- Receive systemic steroid in past 3 months
- Established adrenal insufficiency
- Currently used in chemotherapy or immunosuppressive agents
- Radiotherapy currently received
- Known HIV infection
- Pregnancy
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2017
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT02266264
Start Date
October 1 2014
End Date
May 1 2017
Last Update
October 6 2017
Active Locations (1)
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1
Department of Medicine, Faculty of Medicine, Srinakharinwirot University
Ongkharak, Changwat Nakhon Nayok, Thailand, 26120