Status:
COMPLETED
Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort Study
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Off-spring Cancer Risk
Eligibility:
FEMALE
21-40 years
Phase:
NA
Brief Summary
Parental one-carbon nutrient intake (folic acid and choline) and the genetic polymorphisms of one-carbon metabolic enzyme were interact with regulating embryonic one-carbon metabolic environment, affe...
Eligibility Criteria
Inclusion
- Healthy pregnant women aged 21-40 years with first and single fetal pregnancy
- Healthy pregnant women aged 21-40 years with first and single fetal pregnancy and lineal relative had diabetes
- Healthy pregnant women aged 21-40 years with first and single fetal pregnancy and lineal relative had cancer
- Healthy pregnant women, who are overweight/obesity (pre-pregnancy BMI≧24 kg/m2) or her lineal relative with overweight/obesity, aged 21-40 years with first and single fetal pregnancy.
Exclusion
- Pregnant women who had heart disease, kidney disease, cancer or accepting medical treatment
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2017
Estimated Enrollment :
118 Patients enrolled
Trial Details
Trial ID
NCT02266641
Start Date
October 1 2014
End Date
December 1 2017
Last Update
February 1 2018
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taiwan, 100