Status:
COMPLETED
Contingency Management, Quitting Smoking, and ADHD
Lead Sponsor:
Duke University
Collaborating Sponsors:
National Institute on Drug Abuse (NIDA)
Conditions:
Cigarette Smoking
Smoking Cessation
Eligibility:
All Genders
18-55 years
Phase:
PHASE1
Brief Summary
The overall goal of the study is to evaluate how motivation and readiness for change are influenced in the context of a smoking cessation attempt. A total of 60 adult (i.e. age 18-55) smokers (N=40 wi...
Detailed Description
Individuals with ADHD have altered reinforcement/motivational functioning that are likely related to risk for smoking and recalcitrance for quitting. The investigators lab has demonstrated that the ab...
Eligibility Criteria
Inclusion
- 18-55 years of age
- Male or female; if female of child-bearing potential, must be using an acceptable form of contraception
- ADHD Diagnosis:
- For ADHD Groups: confirmed primary diagnosis, any subtype as determined by the clinician administered CAADID and clinical interview
- For Control Group: NO diagnosis of ADHD as determined by clinician administered CAADID and clinical interview
- ADHD Symptom Ratings:
- For ADHD Groups: T-Score \> 65 on one of the DSM-IV relevant scales (Inattentive Symptoms, Hyperactive-Impulsive Symptoms, Total Symptoms or ADHD Index) on both the Self-Report and Observer versions of the CAARS
- For Control Group: T-Score \< 60 on all of the DSM-IV relevant scales (Inattentive Symptoms, Hyperactive-Impulsive Symptoms, Total Symptoms or ADHD Index) on both the Self-Report and Observer versions of the CAARS
- Self-report smoking at least 10 cigarettes/day
- Provides an afternoon exhaled carbon monoxide reading of at least 10 ppm.
- Cognitive functioning \> 80 as assessed by the KBIT-II
Exclusion
- History of chronic/significant medical condition
- Use of any psychoactive medication in the past 12 months, other than FDA-approved medication for the ADHD group only
- Estimated IQ \< 80 on Kaufmann Brief Intelligence Test, Second Edition
- Has a primary diagnosis of any other Axis I Disorder (determined by the Structured Diagnostic Interview for DSM; SCID) that is significantly impairing and would contraindicate participation in the present study
- Has a primary diagnosis of any Axis II Disorder
Key Trial Info
Start Date :
October 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 8 2017
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT02266784
Start Date
October 1 2014
End Date
December 8 2017
Last Update
October 19 2020
Active Locations (1)
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1
Duke Child and Family Study Center
Durham, North Carolina, United States, 27705