Status:
COMPLETED
The Role of Perioperative Ventilation (Gas Exchange) During Intrabdominal Surgery on Cognitive Function
Lead Sponsor:
Northern State Medical University
Conditions:
Response to Hyperoxia
Hypocapnia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Abdominal surgery commonly requires perioperative relaxation and therefore controlled mechanical ventilation. However, respiratory support can be associated with minor, yet clinically significant chan...
Detailed Description
The moderate hyperventilation resulting in hypocapnia as well as hyperoxia are common features of mechanical ventilation during general anesthesia. While mild hyperventilation is routinely advocated i...
Eligibility Criteria
Inclusion
- Informed consent
- Age \> 18 years and below 80 yrs
- Elective abdominal endoscopic intervention
Exclusion
- Known cerebral disorder, incl. traumatic injury and severe vascular impairment
- Known psychiatric illness
- Severe drug or alcohol abuse
- Resent stroke (during last 6 months)
- Pregnancy
- Within the 30 days prior to this study, either entry into any other randomized therapeutic study of an agent not licensed for the intended use or administration of any other investigational agent for the treatment of ALI. Patients must not participate in such studies for at least 30 days after enrolment into this study.
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2016
Estimated Enrollment :
109 Patients enrolled
Trial Details
Trial ID
NCT02267031
Start Date
October 1 2012
End Date
August 1 2016
Last Update
September 22 2016
Active Locations (1)
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1
City hospital # 1 / Northern State Medical University,
Arkhangelsk, Russia, 163001