Status:
COMPLETED
Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Schizophrenia
Schizophreniform Disorder
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
This is a randomized controlled 6-month trial of the efficacy of a novel intervention combining neuroplasticity-based cognitive training with aerobic exercise, compared to the same systematic cognitiv...
Detailed Description
The Cognitive Training and Exercise intervention involves 24 weeks of systematic computerized cognitive training, 4 hours per week, plus aerobic exercise, four 30 minute sessions per week. The first 1...
Eligibility Criteria
Inclusion
- a first episode of a psychotic illness that began within the past two years;
- a diagnosis by Diagnostic and Statistical Manual of Mental Disorders of schizophrenia, schizoaffective disorder, mainly depressed type, or schizophreniform disorder;
- between 18 and 45 years of age;
- sufficient acculturation and fluency in the English language to avoid invalidating research measures of thought, language, and speech disorder or of verbal cognitive abilities; and
- residence within commuting distance of the Aftercare Research Program at the University of California, Los Angeles.
Exclusion
- evidence of a known neurological disorder (e.g., epilepsy) or significant head injury;
- evidence of alcohol or substance use disorder within the six months prior to the first episode and evidence that substance abuse triggered the psychotic episode or makes the schizophrenia diagnosis ambiguous;
- mental retardation, i.e. premorbid intelligence quotient less than 70.
Key Trial Info
Start Date :
November 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2017
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT02267070
Start Date
November 1 2013
End Date
July 1 2017
Last Update
December 7 2017
Active Locations (1)
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1
University of California, Los Angeles
Los Angeles, California, United States, 90095-6968