Status:

RECRUITING

Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections

Lead Sponsor:

Boston Children's Hospital

Conditions:

Laboratory-confirmed Bloodstream Infection

Central Line-associated Bloodstream Infections

Eligibility:

All Genders

Brief Summary

Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality. This study will attempt to ide...

Detailed Description

This is a prospective cohort pilot study at Boston Children's Hospital (BCH) that will explore the source of presumed CLABSI, which we believe may actually have multiple possible sources including MBI...

Eligibility Criteria

Inclusion

  • Hospitalized at Boston Children's Hospital
  • Central venous catheter of any type including peripherally inserted central catheters (PICC) in any location.
  • Laboratory-confirmed bloodstream infection (LCBI) diagnosed by a clinical blood culture growing certain Gram-negative rods

Exclusion

  • Patients with CDC-defined secondary bloodstream infections

Key Trial Info

Start Date :

November 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT02271243

Start Date

November 1 2014

End Date

December 1 2025

Last Update

January 10 2024

Active Locations (1)

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1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115