Status:
UNKNOWN
Acrosome Reaction Induction Prior to ICSI
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Agence de La Biomédecine
Conditions:
Assisted Reproductive Technique
ICSI
Eligibility:
All Genders
18-43 years
Phase:
NA
Brief Summary
Introduction To get through the egg vestment and fertilize the oocyte, the spermatozoon uses its acrosomal enzymes. When Intracytoplasmic sperm microinjection (ICSI) is performed, the acrosomal enzyme...
Detailed Description
1. Introduction Intracytoplasmic sperm microinjection (ICSI) produces 70% of fertilized oocytes and zygotes which mostly develop normally. To perform ICSI, a spermatozoon is taken from a sperm suspens...
Eligibility Criteria
Inclusion
- Couples involved in an ICSI program
- First attempt only
- Cohort with at least 6 oocytes
Exclusion
- No social security number
- No signed consent form
- Surgically retrieved sperm
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2016
Estimated Enrollment :
620 Patients enrolled
Trial Details
Trial ID
NCT02271490
Start Date
June 1 2014
End Date
October 1 2016
Last Update
October 16 2015
Active Locations (1)
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1
Hôpital Cochin
Paris, France, 75014