Status:
COMPLETED
The Prevalence and Clinical Characteristics of Children With Local Allergic Rhinitis
Lead Sponsor:
Mahidol University
Conditions:
Other Allergic Rhinitis
Eligibility:
All Genders
8-18 years
Phase:
NA
Brief Summary
* To determine prevalence of local allergic rhinitis (LAR) * To evaluate clinical characteristic and severity of local allergic rhinitis * To measure changing of tryptase and Specific IgE for Dermatop...
Detailed Description
Children 8-18 years with NAR were recruited. A NAPT with Der p 1 solutions (NAPT-DP) at 200 AU/mL, 600 AU/mL and 2000 AU/mL at 15-minute interval was performed, respectively. The immediate responses t...
Eligibility Criteria
Inclusion
- Children 8-15 years who were diagnosed with nonallergic rhinitis (NAR) at least 1 year
- No respiratory infections in the previous 4 weeks
- No following treatment of
- systemic corticosteroid 4 weeks
- intranasal corticosteroid 2 weeks
- oral antihistamine 1 week
- leukotriene antagonist 1 week
Exclusion
- Patients with underlying disease:
- chronic rhinosinusitis and nasal polyp
- immunological disease
- chronic renal disease
- hepatobiliary disease
- cardiovascular disease
- cancer
- Parental withdraw consent
- Patient with uncontrolled asthma, peak expiratory flow rate (PEFR) \< 80% of predicted
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2016
Estimated Enrollment :
53 Patients enrolled
Trial Details
Trial ID
NCT02271620
Start Date
January 1 2014
End Date
April 1 2016
Last Update
March 22 2018
Active Locations (2)
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1
Division of allergy and immunology, Department of pediatric, Siriraj Hospital
Bangkoknoi, Bangkok, Thailand, 10700
2
Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University
Bangkok, Thailand, 10700