Status:
COMPLETED
Effects of Propofol on Early Recovery of Hunger After Surgery
Lead Sponsor:
University Hospital, Rouen
Collaborating Sponsors:
Centre Henri Becquerel
Conditions:
Ambulatory Surgery
Anesthesia
Eligibility:
FEMALE
18-45 years
Phase:
PHASE4
Brief Summary
Recovery of hunger is a source of comfort for patients after general anesthesia. Moreover, this aspect of post-operative period is often required for discharging patients from hospital after ambulator...
Eligibility Criteria
Inclusion
- 18-45 years old women
- American Society of Anesthesiologists (ASA) score 1-2
- Affiliated to a social security system
- Undergoing an ambulatory surgery during more than 15 minutes with general anesthesia and control of upper airways (tracheal intubation or supraglottic mask or facial mask ventilation) for oocytes punction before in vitro fertilization
- General anesthesia occuring between 8 and 10 am with respect of pre-operative fasting rules
- APFEL risk score for nausea and vomiting ≤ 2/4
- Ability to understand and read french
- Signature of understood consent
Exclusion
- Other surgery than oocytes punction
- Cognitive dysfunction
- Undernutrition or risk factor of undernutrition (evolutive neoplasia, chronic alcoholism …)
- BMI ≥ 35 kg/m²
- Eating disorders
- Diabetes mellitus
- Chronic treatment with drugs modifying feeding behavior :
- Benzodiazepines
- Inhibitors of serotonin reuptake
- Others
- Non respect of pre-operative fasting rules
- Indication for rapid sequence induction (gastro-oesophageal reflux, absence of gastric emptying …)
- Contraindication to propofol (allergia to propofol, soybean or peanuts, past history of propofol infusion syndrome, unstable cardiovascular disease) or to sevoflurane (past history of malignant hyperthermia, epilepsy or liver disorders after administration of a halogenated anesthetic)
- Pregnant or breastfeeding woman
- Involvement in another clinical trial under 4 previous weeks
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2016
Estimated Enrollment :
116 Patients enrolled
Trial Details
Trial ID
NCT02272166
Start Date
November 1 2014
End Date
July 1 2016
Last Update
December 21 2017
Active Locations (1)
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1
Rouen University Hospital
Rouen, France, 76031