Status:
COMPLETED
Neurophysiological Assessment of Healthy and Impaired Human Lower Urinary Tract Function
Lead Sponsor:
Ulrich Mehnert
Conditions:
Lower Urinary Tract Symptoms
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
Study part 1 will consist of sensory evoked cortical potential (SEP) measurements of the lower urinary tract (LUT) in healthy subjects using different stimulation frequencies from 0.25 to 3Hz to find ...
Eligibility Criteria
Inclusion
- healthy volunteers:
- Written informed consent,
- good mental and physical health,
- age \>18y,
- Patients with LUTS and Patients with LUTS and treatment:
- Written informed consent,
- age \>18y,
- prior urodynamic investigation,
- LUTS since \>6months with or without detrusor overactivity
Exclusion
- healthy volunteers:
- any neurological or urological pathology,
- current pregnancy or lactation,
- urinary tract infection,
- hematuria,
- any previous pelvic or spine or craniocerebral surgery,
- any anatomical anomaly of the LUT or genitalia,
- any metabolic disease,
- any LUT malignancy,
- bladder capacity \<150mL,
- SDV at 60mL;
- Patients with LUTS and Patients with LUTS and treatment:
- current pregnancy or lactation,
- urinary tract infection,
- gross hematuria
Key Trial Info
Start Date :
May 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT02272309
Start Date
May 1 2014
End Date
December 31 2023
Last Update
January 9 2025
Active Locations (1)
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1
Universitätsklinik Balgrist
Zurich, Canton of Zurich, Switzerland, 8008