Status:

COMPLETED

Pharmacokinetics and Safety of Asasantin Extended Release (RAD-SP) Capsules in Japanese Healthy Male Volunteers

Lead Sponsor:

Boehringer Ingelheim

Conditions:

Healthy

Eligibility:

MALE

20-35 years

Phase:

PHASE1

Brief Summary

Study to investigate pharmacokinetics, pharmacodynamics and safety of RAD-SP capsule in multiple administration to healthy adult male volunteers.

Eligibility Criteria

Inclusion

  • Healthy male volunteers judged by the investigator as appropriate subjects on the basis of screening test results
  • Age range: ≥ 20 years and ≤ 35 years
  • Body weight between 50 and 80 kg
  • Obesity is within ± 20% of the standard body weight
  • Ability to provide written informed consent to participate in the study

Exclusion

  • History of drug allergy
  • History of bronchial asthma
  • History of drug abuse and alcohol abuse
  • History of hemorrhagic tendency or hemorrhagic disease
  • Volunteers who have experiences in playing sports such as boxing which may damage the brain
  • Accidents associated with brain concussion and contusion (traffic accident, etc.)
  • Administration of other study drug within 4 months before start of administration of this study drug
  • Collection of whole blood (≥ 400 ml) within 3 months before study drug administration
  • Collection of component blood (≥ 400 ml) within 1 months before study drug administration
  • Intake of some drug or other within 10 days before the study drug administration
  • Excessive physical activities within the last 5 days prior to study drug administration
  • Intake of alcohol within 3 days before study drug administration
  • Volunteers judged by the investigator to be inappropriate as the subjects of study

Key Trial Info

Start Date :

July 1 1999

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT02273479

Start Date

July 1 1999

Last Update

October 24 2014

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