Status:
UNKNOWN
Pharmacologically Active Constituents of Chocolate and Their Symptomatic Effects in Patients With Idiopathic Parkinson's Disease
Lead Sponsor:
Technische Universität Dresden
Collaborating Sponsors:
University of Wuerzburg
Conditions:
Parkinson Disease
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
This study evaluates plasma concentrations of pharmacologically active constituents of chocolate and their effects on motor and non-motor symptoms of Parkinson's disease. Following one week of abstine...
Eligibility Criteria
Inclusion
- Female or male individuals aged 40 years and above
- Parkinson's Disease according to the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria
- Hoehn and Yahr stage I-III
- Minimum score of 16 points in the motor part of the Unified Parkinson Disease Rating Scale (UPDRS part III)
- Stable antiparkinsonian medication for at least 4 weeks prior to study inclusion
- Ability to provide informed consent
Exclusion
- Clinical signs for a secondary or atypical Parkinsonian syndrome
- Treatment with any investigational medical product within 30 days prior to study inclusion
- Intake of chocolate or other cocoa-containing products within the last 7 days prior to study inclusion (patients can be re-screened after 7 days of abstinence from chocolate and other cocoa-containing products)
- Known intolerance or allergies against chocolate or other cocoa-containing products
- Diabetes mellitus and/or impaired glucose tolerance in the medical history
- Alcohol or drug abuse in the medical history
- Presence of levodopa-induced motor complications
- Other neurological, psychiatric or miscellaneous conditions that would significantly impair study participation, medical assessments or the consenting process
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2015
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT02275884
Start Date
June 1 2013
End Date
June 1 2015
Last Update
October 27 2014
Active Locations (1)
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1
Department of Neurology, Dresden University of Technology
Dresden, Saxony, Germany, 01307