Status:
COMPLETED
Effects of VSL#3 on Neuro-cognitive Profile of HIV Patients
Lead Sponsor:
Azienda Policlinico Umberto I
Conditions:
HIV Seropositivity
ART
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Aim of the study is to evaluate the effects of a change in the intestinal microflora on the neuro-cognitive profile of patients with HIV infection receiving HAART treatment. Improvements will be evalu...
Detailed Description
The HIV virus has a marked tropism for the central nervous system. In 1986, the term AIDS Dementia Complex (ADC) has been coined which includes in a single syndrome, a whole series of severe neurologi...
Eligibility Criteria
Inclusion
- Men or women at least 18 years of age
- In HAART with HIV RNA \<50cp/mL, with CD4 counts\> 400 cells / mm
- Availability to release informed consent
Exclusion
- Patients with known allergy or intolerance to VSL#3
- Chronic inflammatory bowel diseases
- Drug addiction
- Use of antibiotics or probiotics during the 3 weeks prior the enrollment
- Pregnancy
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT02276326
Start Date
July 1 2014
End Date
June 1 2019
Last Update
February 8 2023
Active Locations (1)
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1
Policlinico Umberto I Hospital
Rome, Italy, 00155