Status:
COMPLETED
Comparative Study of Specular Microscopes for Measurements of Cell Density, Coefficient of Variation and Hexagonality
Lead Sponsor:
Nidek Co. LTD.
Conditions:
Corneal Endothelial Cell Loss
Eligibility:
All Genders
18-80 years
Brief Summary
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Nidek CEM-530 Center point method and Corner point method. The secondary objective ...
Detailed Description
The primary objective of this clinical study is to collect clinical data to support an FDA 510(k) submission for the Nidek CEM-530 Center point method and Corner point method.
Eligibility Criteria
Inclusion
- Non-Pathologic: Male or female subjects from 18 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site,and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study.
- Pathologic: Male and female subjects from 29 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site, and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study. At least one eye with any of the following conditions:
- History of post-op surgical trauma including bullous keratopathy
- History of corneal transplant
- Physical injury or trauma to the cornea
- Long term Fuch's dystrophy, Guttata or other corneal endothelial dystrophies
- Keratoconus
- Long term PMMA contact lens use (greater than 3 years)
Exclusion
- Non-Pathologic: Male and female subjects from 29 to 80 years old who have full legal capacity to volunteer on the date the informed consent is signed. Subjects who can follow the instructions by the clinical staff at the clinical site, and can attend examinations on the scheduled examination date. Subjects who agree to participate in the study. At least one eye with any of the following conditions:
- History of post-op surgical trauma including bullous keratopathy
- History of corneal transplant
- Physical injury or trauma to the cornea
- Long term Fuch's dystrophy, Guttata or other corneal endothelial dystrophies
- Keratoconus
- Long term PMMA contact lens use (greater than 3 years)
- Pathologic: History of cataract, refractive or ocular surgical procedures that render the cornea opaque or otherwise impact its ability to be imaged using the investigational device. Fixation problems which may prevent obtaining at least poor quality (refer to Figure 1) CEM-530 and KONAN CELLCHEK PLUS images in either eye.
Key Trial Info
Start Date :
September 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT02276638
Start Date
September 1 2014
End Date
October 1 2014
Last Update
March 20 2019
Active Locations (1)
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1
Andover Eye Associates
Andover, Massachusetts, United States, 01810