Status:
UNKNOWN
MRI,Gene And Cognitive Performance Study of Patients With Cerebral White Matter Lesions(WMLs)
Lead Sponsor:
Wei Wang
Conditions:
Cerebral White Matter Lesions
Eligibility:
All Genders
40-85 years
Brief Summary
The purpose of this study is:1)to observe topological organization in brain structural and functional networks in cerebral white matter lesion patients and to evaluate the association between impairme...
Detailed Description
100 patients with cerebral white matter lesions and 100 normal controls will be observed. All of them will receive MRI scan(T1WI,T2WI,T2flair,MRA,SWI,ASL,DTI and fMRI) and the assessment of the neurop...
Eligibility Criteria
Inclusion
- MRI diagnosis of cerebral white matter lesions Must be able to measure his(her) neuropsychologic function No severe stroke history and no physical disability Patients aged 40 to 85 Based on China's relevant laws, the patient himself agreed to participate in this study, a good compliance.Patients himself/herself must sign informed consent moreover
Exclusion
- Unable to undergo examinations due to disturbances of consciousness or medical conditions Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock AD,Parkinson's disease, malignant tumor, MS and other autoimmune diseases toxic and metabolic encephalopathy cerebral white matter lesions caused by CADASIL and other confirmed monogenic disease
Key Trial Info
Start Date :
March 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2019
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT02276976
Start Date
March 1 2014
End Date
September 1 2019
Last Update
December 14 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030