Status:

UNKNOWN

Assessment of Coronary Flow Reserve by PET-H215O and FFR. Comparison With Dynamic Acquisition Using CZT Camera

Lead Sponsor:

University Hospital, Caen

Collaborating Sponsors:

Spectrum Dynamics

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The study will assess coronary flow reserve by PET-H215O and FFR in patients suspected of coroanry artery disease. This a comparative study with dynamic acquisition using CZT camera and 99mcTc-mibi. 2...

Eligibility Criteria

Inclusion

  • Patient between 18 and 80 years
  • Suspected coronary disease and / or coronary syndrome patient ST-
  • Patient who has been informed of the study and has given his informed consent
  • Patient affiliated to a social security system.

Exclusion

  • Patient having no coronary disease at coronary angiography with FFR on the 3 main epicardial arteries (absence of ≥ 50% stenosis of at least one artery)
  • Delay of Care grater than 30 days between the PET and SPECT imaging and the diagnostic coronary angiography
  • Patient with a recent history of myocardial infarction and STEMI, unstable angina
  • Patient with extra-cardiac disease whose prognosis can interfere with the treatment decision
  • Pregnant or lactating women
  • Patient allergic to contrast products during coronary angiography
  • Patient with MDRD clearance les than 60 ml / min
  • Patient Under guardianship, or unable to understand the purpose of the study

Key Trial Info

Start Date :

November 1 2014

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2015

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT02278497

Start Date

November 1 2014

End Date

December 1 2015

Last Update

July 31 2015

Active Locations (1)

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1

Medecine Nucleaire

Caen, France, 14000