Status:
COMPLETED
The Respiratory Physiology Variation of COPD Patients in Inspiratory Muscle Training
Lead Sponsor:
Guangzhou Institute of Respiratory Disease
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
20-80 years
Phase:
PHASE2
PHASE3
Brief Summary
Background：Respiratory muscle weakness is observed in chronic obstructive pulmonary disease(COPD) patients and contributes to hypercapnia, dyspnoea, nocturnal oxygen desaturation and reduced walking d...
Detailed Description
Subjects: COPD group ( experimental group ) Ten subjects with moderate COPD were will be recruited from the investigators outpatient clinic for the study. According to the criteria of the American Th...
Eligibility Criteria
Inclusion
- Severe and very severe COPD (postbronchodilator FEV1/FVC under 70% and FEV1 under 50% of the predicted value
- Inspiratory muscle weakness（Maximal Inspiratory Pressure under 60cmH2O.
- Bronchial dilation test(BDT) negative.
- Exclusion of other cardiopulmonary diseases.
Exclusion
- Suffer from acute exacerbation less than 4 weeks.
- Intravenous or oral corticosteroids in 4 weeks.
- With other heart, lung and brain disorders.
- With poor compliance.
Key Trial Info
Start Date :
June 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT02278523
Start Date
June 1 2014
End Date
October 1 2014
Last Update
October 30 2014
Active Locations (1)
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Respiratory muscle training device
Guangzhou, Guangdong, China, 510000