Status:
ACTIVE_NOT_RECRUITING
Comparison of Regimens MPIB, CIPCEA, PCEA
Lead Sponsor:
KK Women's and Children's Hospital
Conditions:
Breakthrough Pain
Eligibility:
FEMALE
21-50 years
Phase:
PHASE3
Brief Summary
Epidural analgesia is the gold standard of pain relief for labour pain. Despite this, more than 50% of parturients continue to experience pain leading to suffering and increased caregiver workload. Wo...
Detailed Description
The research team developed two novel epidural delivery regimens: computer-integrated PCEA (CIPCEA) and modified programmed intermittent bolus (MPIB) focused on individualization of analgesic requirem...
Eligibility Criteria
Inclusion
- Healthy (ASA physical status 1 and 2) nulliparous parturients at term (≥36 weeks gestation);
- Singleton foetus
- Early labour (cervical dilation ≤5cm)
- Request labour epidural analgesia
- At least 21 years of age
Exclusion
- parturients with multiple pregnancies
- non-cephalic foetal presentation
- obstetric (e.g. pre-eclampsia, premature rupture of amniotic membranes, gestational diabetes on insulin) and uncontrolled medical (e.g. cardiac disease) complications
- have contraindications to neuraxial blockade or have received parenteral opioids with the last 2 hours.
Key Trial Info
Start Date :
January 28 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2026
Estimated Enrollment :
839 Patients enrolled
Trial Details
Trial ID
NCT02278601
Start Date
January 28 2015
End Date
December 31 2026
Last Update
October 9 2024
Active Locations (1)
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1
KK Women's and Children's Hospital
Singapore, Singapore, 229899