Status:
ACTIVE_NOT_RECRUITING
Transdermal Vagal Stimulation for POTS
Lead Sponsor:
Vanderbilt University
Conditions:
Postural Orthostatic Tachycardia Syndrome
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
Some patients experience high heart rates and symptoms of light-headedness, fatigue, headache during standing despite well maintained blood pressure. These patient are disabled and can't be in uprigh...
Detailed Description
Background Postural Tachycardia Syndrome (POTS) is a syndrome characterized by disabling symptoms of inadequate cerebral perfusion on assuming the upright posture, including light-headedness, fatigue,...
Eligibility Criteria
Inclusion
- Non-smoking patients who qualify with the criteria of idiopathic postural tachycardia syndrome will be studied. The criteria are:
- an increase of heart rate of 30 beats/minute or an upright heart rate of \>= 120 bpm, and
- chronic problems of symptoms during upright posture for at least 6 month.
- Subjects must also be able to safely withdrawn from medications that influence heart rate, blood pressure, and hormone levels that regulate blood pressure.
- The age limit is 18-75 years.
Exclusion
- Patients that have other major medical problems, such as cancer or heart disease are excluded because the influence of that diagnosis on the symptoms is not known.
- Pregnancy.
Key Trial Info
Start Date :
June 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2025
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT02281097
Start Date
June 1 2013
End Date
December 31 2025
Last Update
February 5 2025
Active Locations (1)
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1
Autonomic Dysfunction Center, Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232-2195