Status:

COMPLETED

NGS Genome Analysis in Personalisation of Lung Cancer Treatment

Lead Sponsor:

Centre Georges Francois Leclerc

Conditions:

Lung Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The identification of driver mutations in the epidermal growth factor receptor (EGFR) as the primary oncogenic event in a subset of lung adenocarcinomas led to a model of targeted treatment and geneti...

Eligibility Criteria

Inclusion

  • patients of bronchial adénocarcinoma with metastases can benefit from first-line therapy - targeted therapy by tyrosine kinase inhibitor(TKI) for EGFR mutation and chemotherapy for non EGFR mutation)
  • Patients with epidermoid cancer of the lungs can benefit from chemotherapy
  • man and women
  • age ≥ 18 years
  • Patients have signed a written informed consent form
  • Patients are affiliated to s social health insurance

Exclusion

  • Survival time ≤ 3 months
  • Patients with cerebral metastases
  • Patients could not benefit from treatment for others diseases
  • Pregnancy or breast-feeding
  • Incapacity to sign the consent form for psychiatric, behavioural disorders
  • Private individuals of freedom or under tutelage

Key Trial Info

Start Date :

October 24 2014

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 17 2018

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT02281214

Start Date

October 24 2014

End Date

November 17 2018

Last Update

January 4 2019

Active Locations (1)

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Centre Georges François Leclerc

Dijon, France, 21000