Status:

UNKNOWN

Substudy : Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Lead Sponsor:

Laval University

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Chronic Obstructive Pulmonary Disease

Eligibility:

All Genders

50-75 years

Brief Summary

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Its prevalence is in progression and COPD is expected to become the fourth leading cause of death ...

Detailed Description

Focusing our attention during exacerbations, a period of aggravated systemic inflammation, should be more rewarding in terms of understanding the link between inflammation burst and muscle disease in ...

Eligibility Criteria

Inclusion

  • male and female
  • COPD with an FEV1 of under 60% of predicted
  • non-smoker
  • between 50 and 75 years old
  • experiencing an acute exacerbation of COPD (24-48 hours, before treatment)

Exclusion

  • all inflammatory disease (HIV, cancer, renal and cardiac deficiency)
  • hormonal dysregulation
  • inferior limb pathology
  • neuromuscular pathology
  • history of tobacco or alcool abuse
  • oxygen dependent

Key Trial Info

Start Date :

May 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2018

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT02282436

Start Date

May 1 2012

End Date

May 1 2018

Last Update

September 8 2016

Active Locations (1)

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Centre de recherche de l'Institut de cardiologie et de pneumologie de Québec

Québec, Quebec, Canada, G1V 4G5