Status:
COMPLETED
The Effect of Dietary Salt Intake on Immune Function in Patients With Multiple Sclerosis
Lead Sponsor:
Yale University
Conditions:
Multiple Sclerosis
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The purpose of this work is to investigate the influence of dietary salt intake on immune function in multiple sclerosis (MS) subjects and healthy controls. This study primarily tests the hypothesis t...
Detailed Description
The purpose of this work is to investigate the influence of dietary salt intake on immune function in MS subjects and healthy controls. This study primarily tests the hypothesis that higher dietary sa...
Eligibility Criteria
Inclusion
- Male or Female adult subjects
- Ages 18-60, inclusive
- diagnosis of CIS or MS by 2010 McDonald Criteria (in the case of MS subjects)
- Naive to FDA- approved MS therapies such as glatiramer acetate, interferon-beta, natalizumab, fingolimod, tecfidera, or teriflunomide
Exclusion
- Secondary or primary progressive MS
- Prior exposure to FDA-approved MS therapies or chemotherapies of any kind
- Known history of autoimmune disease besides MS
- Known history of renal disease, hypertension or congestive heart failure
- Currently taking medications that could affect urine sodium excretion (e.g. diuretics or others that act on the renin-angiotensins-aldosterone system)
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 8 2019
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT02282878
Start Date
September 1 2014
End Date
December 8 2019
Last Update
April 19 2021
Active Locations (1)
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1
Yale MS Center
New Haven, Connecticut, United States, 06519