Status:
UNKNOWN
Effect of Genetic Association With Functional Dyspepsia and Mood Disorders
Lead Sponsor:
Chinese University of Hong Kong
Conditions:
Dyspepsia
Eligibility:
All Genders
18-60 years
Brief Summary
Background: Functional dyspepsia (FD) is one of the commonest digestive disorders. The pathophysiology of functional dyspepsia is uncertain. Risk factors include genetics, gender, age, helicobacter p...
Detailed Description
Methods: All subjects will participate in (1) Demographic assessment, (2) Questionnaires administration and (3) Blood sample collection. The three steps must be completed within 2 weeks. 1. Demograp...
Eligibility Criteria
Inclusion
- All subject
- Age 18-60
- Provision of written consent
- Additional to FD patient
- Symptoms fulfilling Rome III criteria of functional dyspepsia
- Negative upper endoscopy (oesophagogastroduodenoscopy or OGD) finding
Exclusion
- All subject
- History of cancer
- Diabetes mellitus
- History of gastric surgery
- Acid suppressants or medications that affect motility in past 4 weeks
- Organic disease as cause of dyspepsia (for subjects with dyspeptic symptom)
- Additional to healthy volunteer
- • Any gastrointestinal symptoms (including acid regurgitation, heartburn, epigastric pain, bloating sensation, constipation, abdominal pain, diarrhea) in the past 4 weeks
- Additional to FD patient
- Frequent (once or more per week) acid reflux or heartburn symptoms
- Helicobacter pylori (Hp) infection
Key Trial Info
Start Date :
August 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2017
Estimated Enrollment :
1200 Patients enrolled
Trial Details
Trial ID
NCT02282995
Start Date
August 1 2012
End Date
December 1 2017
Last Update
April 25 2017
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Prince of Wales Hospital
Hong Kong, Hong Kong