Status:
COMPLETED
Efficacy of Locally Delivred 1.2% Rosuvastatin Gel in Chronic Periodontitis
Lead Sponsor:
Government Dental College and Research Institute, Bangalore
Conditions:
Chronic Periodontitis
Eligibility:
All Genders
22-55 years
Phase:
PHASE2
PHASE3
Brief Summary
BACKGROUND: Chronic periodontitis (CP) is an inflammatory condition affecting tooth supporting tissues and alveolar bone that surround the tooth leading to formation of deepend gingival sulcus that is...
Detailed Description
Rosuvastatin (RSV) is one of new synthetic, second-generation, sulfur-containing, hydrophilic statin, a highly efficient competitive inhibitors of HMG CoA Reductase having important role in reducing s...
Eligibility Criteria
Inclusion
- Systemically sound with moderate probing depth (PD) of 5- 6 mm or clinical attachment loss (CAL) of 4 - 6 mm) or deep pockets (PD ≥ 7 mm or CAL of 6 - 9 mm) and vertical bone loss ≥ 3 mm on intraoral periapical radiographs.
- Subjects with ≥ 20 teeth with no history of periodontal therapy in the preceding 6 months nor under any antibiotic therapy were included in the study.
Exclusion
- Patients on systemic statin therapy with known or suspected allergy to the RSV group, patients with any other forms of periodontitis, use of tobacoo in any form, smokers, alcoholics, immune-compromised and systemically unhealthy patients, and pregnant or lactating females were excluded.
Key Trial Info
Start Date :
January 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT02283515
Start Date
January 1 2014
End Date
June 1 2014
Last Update
November 5 2014
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