Status:
COMPLETED
Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine
Lead Sponsor:
Mahidol University
Conditions:
Post Operative Pain
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.
Detailed Description
The participants are randomized into two groups by computer randomization. The patient undergo spinal anesthesia with 0.5% Heavy bupivacaine with morphine 0.2 mg. IV PCA morphine is initiate in the po...
Eligibility Criteria
Inclusion
- ASA classification 1-2 undergoing abdominal hysterectomy with/without salpingo-oophorectomy under spinal anesthesia with intrathecal morphine
- Patient can use patient-controlled analgesia (IV PCA)
Exclusion
- History of drug allergy to gabapentinoid and related drug
- History of regular analgesic drug use, psychiatric drug usage, drug abuse, alcohol addiction or chronic pain patient
- Renal disease (Creatinine Clearance \< 60), Liver disease, Seizure disorder and Psychiatric disorder
Key Trial Info
Start Date :
November 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2016
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT02285010
Start Date
November 1 2014
End Date
August 1 2016
Last Update
March 15 2019
Active Locations (1)
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1
Faculty of Medicine Siriraj Hospital
Bangkoknoi, Bangkok, Thailand, 10700