Status:
COMPLETED
A Phase IV Study Investigating the Effects of Remifentanil Concentrations on Propofol Requirements for Loss of Consciousness, Response to Painful Stimuli, Bispectral Index and Associated Haemodynamic Changes
Lead Sponsor:
The University of Hong Kong
Conditions:
Induction of Anaesthesia
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
A prospective, randomised, phase IV trial including 150 patients. To evaluate the effects of varied concentrations of remifentanil on the proposal requirements for the loss of consciousness and respo...
Detailed Description
BackGround The combination of remifentanil and propofol infusions is a widely used method of total intravenous anaesthesia. (1) Target controlled infusion (TCI) is a pharmacokinetic (PK) infusion sys...
Eligibility Criteria
Inclusion
- ASA I or II patients (healthy or with mild systemic illness) undergoing planned surgery requiring general anaesthetic
Exclusion
- Subjects with pre-existing neurological or psychiatric illness.
- Subjects on CNS acting medication or analgesics.
Key Trial Info
Start Date :
February 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT02287181
Start Date
February 1 2015
End Date
August 1 2015
Last Update
March 11 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Queen Mary Hospital
Pok Fu Lam, Hong Kong