Status:
UNKNOWN
Genetic and Morphological Analysis of Thyrotoxic Periodic Paralysis
Lead Sponsor:
West China Hospital
Conditions:
Thyrotoxic Periodic Paralysis
Eligibility:
MALE
20-60 years
Brief Summary
The study aims to analyze the genetic variance between thyrotoxic periodic paralysis (TPP) patients and pure hyperthyroidism individuals. Meanwhile, the investigators also intended to evaluate the mor...
Detailed Description
Chinese males of their third and forth decades are extremely predisposed to periodic paralysis when they are hyperthyroid. Due to their imbalanced predilection to the disease, genetic variance is cons...
Eligibility Criteria
Inclusion
- A recent history(within three months) of acute limb muscle weakness, hypokalemia and decreased TSH with elevated free FT4, FT3.
Exclusion
- Hyperthyroid myopathy with long term muscle weakness, family periodic paralysis, renal tubular acidosis, hyperaldosteronism, hemiplegia, paraplegia, or any history of other metabolic or traumatic muscular disease,
Key Trial Info
Start Date :
October 1 2014
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2017
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT02287363
Start Date
October 1 2014
End Date
October 1 2017
Last Update
November 10 2014
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