Status:
COMPLETED
Prebiotics Change Microflora and Decrease LPS
Lead Sponsor:
Institut Pasteur de Lille
Collaborating Sponsors:
Institut Polytechnique LaSalle Beauvais
Conditions:
Prebiotics Effect
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the present study was to establish the prebiotic effect of a new xylo-oligosaccharides (XOS) and of an inulin-and-XOS mixture (INU-XOS) and to determine their effect on endotoxaemia (li...
Detailed Description
The study followed a randomized, parallel placebo-controlled double-blind design. A semi-quantitative dietary survey was performed at enrollment in order to assess the usual dietary fiber intake in o...
Eligibility Criteria
Inclusion
- Stable weight (+/- 3 kg) for the last 3 months
- Body Mass Index (BMI) between 18.5 and 27 kg/m²
- Consuming between 13 and 18 g of dietary fiber a day
- Student on campus at the Institut Polytechnique LaSalle Beauvais
- Informed consent form signed
- Able to follow the requirement of the study
- Have a social security
Exclusion
- Has a serious pathology
- Has a gastrointestinal, vesicular or pancreatic disease
- Took an antibiotic or a laxative treatment in the last 6 months
- Surgery of the gastrointestinal tract in the last 12 months
- Orange juice intolerance
- Chronic or recurring diarrhea, constipation or abdominal pain
- Taking drugs known to have an effect on the gastrointestinal, pancreatic and vesicular function
- Recent gastroenteritis or foodborne illness
- Diabetes
- Consuming regularly of probiotics- or prebiotics-enriched products in the last month
- Drinking more than 3 glasses of alcohol a day
- Is deprived of liberty
- Is under judicial protection
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT02287844
Start Date
October 1 2008
End Date
December 1 2008
Last Update
November 17 2014
Active Locations (1)
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1
Institut Polytechnique LaSalle Beauvais
Beauvais, Oise, France, 60000