Status:

RECRUITING

DOvEEgene/WISE Genomics: Diagnosing Ovarian and Endometrial Cancer Early Using Genomics

Lead Sponsor:

McGill University

Collaborating Sponsors:

McGill University Health Centre/Research Institute of the McGill University Health Centre

Conditions:

Ovarian Neoplasms

Endometrial Neoplasms

Eligibility:

FEMALE

18+ years

Brief Summary

This study aims to develop and validate a test for detecting ovarian and endometrial cancers early. It relies on detecting somatic mutations that are associated with these cancers from a uterine pap t...

Detailed Description

For women in high-income countries, ovarian/fallopian tube and endometrial cancers are within the top four cancers in terms of incidence, death and healthcare expenditure. The deaths associated with t...

Eligibility Criteria

Inclusion

  • Case Inclusion:
  • Subjects should have suspected or confirmed cancer of the upper genital tract.
  • Participant will undergo surgery for tumour removal.
  • Control inclusion:
  • • Subjects should be scheduled to have a hysterectomy, bilateral salpingectomy, with or without bilateral oophorectomy, for presumed benign disease.

Exclusion

    Key Trial Info

    Start Date :

    January 1 2014

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    October 1 2026

    Estimated Enrollment :

    1200 Patients enrolled

    Trial Details

    Trial ID

    NCT02288676

    Start Date

    January 1 2014

    End Date

    October 1 2026

    Last Update

    June 18 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Royal Victoria Hospital (Glen Site)

    Montreal, Quebec, Canada, H4A 3J1