Status:

TERMINATED

Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome

Lead Sponsor:

Milton S. Hershey Medical Center

Conditions:

Down Syndrome

Eligibility:

All Genders

2-17 years

Brief Summary

About 1 in every 700 babies born in the United States has Down's Syndrome (DS; Trisomy 21), 99% of whom have some degree of intellectual disability. Recent advances in medicine have resulted in a dram...

Detailed Description

Based on the Valkenburg group's study (2009), one might hypothesize that if the BIS value is fixed for all patients, then a patient with an intellectual disability such as a patient with DS would requ...

Eligibility Criteria

Inclusion

  • • Patients with DS and those without DS receiving BIS monitoring
  • Children between the ages of 2 and 17 years old (inclusive)
  • Patients scheduled for unilateral or bilateral tympanostomy (ear tube placement) at Penn State Hershey Medical Center
  • Patients with American Society of Anesthesiologists (ASA) physical status I, II and III
  • Eligible for standard general anesthesia technique protocol as determined by anesthesia provider(s)

Exclusion

  • Patients with congenital diseases/anomalies except Down's Syndrome
  • Patients with myotonic dystrophies or other neurodegenerative diseases
  • Patients with cerebrovascular accidents (strokes)
  • Patients not receiving BIS monitoring
  • Pregnant patients
  • Patients with allergic skin reactions to electrode patches
  • Patients 18 years of age and greater

Key Trial Info

Start Date :

October 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 13 2017

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT02288702

Start Date

October 1 2014

End Date

July 13 2017

Last Update

January 23 2023

Active Locations (1)

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Hershey Medical Center

Hershey, Pennsylvania, United States, 17033