Status:
TERMINATED
Spot Urinary Analysis to Assess Loop Diuretic Efficiency in Stable Heart Failure
Lead Sponsor:
Hasselt University
Collaborating Sponsors:
Ziekenhuis Oost-Limburg
Conditions:
Heart Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The primary objective of this study is to assess whether the urinary sodium/creatinine or chloride/creatinine ratio might predict successful downtitration of loop diuretics in patients with stable hea...
Eligibility Criteria
Inclusion
- Patient has a left ventricular ejection fraction \<40% or has been previously hospitalized with a primary diagnosis of heart failure
- Patient receives a daily maintenance dose of loop diuretics
Exclusion
- Patient was hospitalized for heart failure \<3 months before study inclusion
- The maintenance dose of loop diuretics was changed \<3 months before study inclusion
- The maintenance dose of renin-angiotensin-aldosterone system blockers or beta-blocker medication was changed \<3 months before study inclusion
- Cardiac resynchronization therapy (CRT) was initiated \<3 months before study inclusion
- At the moment of inclusion, the patient has either one of the following signs of volume overload: lower leg edema +2/4, ascites, lung congestion
- Patient is not able to measure his/her weight safely and correct at home
Key Trial Info
Start Date :
September 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2016
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT02288819
Start Date
September 1 2014
End Date
April 1 2016
Last Update
April 16 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ziekenhuis Oost-Limburg
Genk, Limburg, Belgium, 3600